Beta-Neoendorphin CAS: 77739-21-0 YS-TYR-PRO-OH YGGFLRKYP

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INOMBOLO YECASS:77739-21-0

Igama:IBeta-Neoendorphin

Ifomula yemichiza:I-C54H77N13O12

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Ukusetyenziswa

I-β-neoendorphin yipeptide ye-opioid engapheliyo kunye nesakhiwo se-peptide elithoba kunye nokulandelelana kwe-amino acid yeTyr-Gly-Gly-Phe - Leu-Arg-Lys-Tyr-Pro (YGGFLRKYP).

I-Beta-neoendorphins (i-beta-nep) inamandla okuvuselela ukuphulukiswa kwesilonda ngokukhawulezisa ukufuduka kwe-keratinocyte.Oku kuphunyezwa nge-beta-Nep activation ye-mitogen activated protein kinase (MAPK) kunye ne-extracellular signal-regulated kinases 1 kunye ne-2 (ERK 1 kunye ne-ERK 2);Kwaye ukulawulwa kwe-matrix metalloproteinases 2 kunye ne-9 (MMP-2 kunye ne-MMP-9).Ukuphulukiswa kwamanxeba kwe-β-NEP kukhokelela ekufudukeni ngaphandle kokuchaphazela ukwanda kweekeratinocytes zabantu.