I-Chemical API Powder Pharama Grade Benzos CAS 39243-02-2 Pyrazolam

I-Chemical API Powder Pharama Grade Benzos CAS 39243-02-2 Isithombe Esifakiwe sePyrazolam

incazelo emfushane:

INOMBOLO YE-CAS:39243-02-2

Igama:I-Pyrazolam

Ifomula yekhemikhali:I-C16H12BrN5

MW:354.2

I-EINECS:200-258-5

Iphoyinti lokuncibilika:253-255 °C

Indawo yokubilisa:544.4±60.0 °C(Kubikezelwe)

ukuminyana :1.62±0.1 g/cm3(Kubikezelwe)

Izinga lokushisa lokulondoloza:-20°C

pKa:2.18±0.40(Kubikezelwe)

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Ukusetshenziswa

I-Pyrazolam

8-Bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine

Ifomethi

Isixazululo se-Pyrazolam

4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine

8-bromo-1-methyl-6-(2-pyridinyl)-

8-Bromo-1-methyl-6-(2-pyridinyl)-4H-[1,2,4]triazolo[4,3-a][1,4]be

nzodiazepine

Incazelo

I-Pyrazolam (SH-I-04) iwumphumela we-benzodiazepine owaqalwa ithimba elaliholwa ngu-Leo Sternbach e-Hoffman-La Roche ngeminyaka yawo-1970.

I-Pyrazolam inokufana kwesakhiwo ne-alprazolam ne-bromazepam.Ngokungafani namanye ama-benzodiazepines, i-pyrazolam ayibonakali ingena ku-metabolism, kunalokho ikhishwa ingashintshiwe emchameni.

Chemical Properties

I-Pyrazolam iyi-benzodiazepine eye yahlukunyezwa ukuzijabulisa.Njengamanye ama-benzodiazepines, i-pyrazolam inemiphumela ye-anxiolytic.

Isebenzisa I-Pyrazolam iyi-benzodiazepine ene-half-life yokuqeda cishe amahora angu-17 futhi awekho ama-metabolite atholakalayo ku-serum yomuntu kanye nomchamo;Ngakho-ke i-pyrazolam ingase ingabonakali ngaphandle kwamasu okuhlaziya amathuluzi.

IsiceloI-Pyrazolam i-benzodiazepine yomklami eye yathengiswa ku-inthanethi 'njengephezulu esemthethweni' noma 'ikhemikhali yocwaningo'.Selokhu yavela eYurophu eminyakeni embalwa edlule, i-pyrazolam, kanye namanye ama-benzodiazepines omklami, aye abhekana nawo ngokwandayo emsebenzini wamacala omthetho.