Chemical API Powder Pharama Grade Benzos CAS 39243-02-2 Pyrazolam

inkcazelo emfutshane:

INOMBOLO YECASS:39243-02-2

Igama:I-Pyrazolam

Ifomula yemichiza:I-C16H12BrN5

MW:354.2

EINECS:200-258-5

Indawo yokunyibilika:253-255 °C

Indawo yokubilisa:544.4±60.0 °C(Kuqikelelwe)

Ubuninzi :1.62±0.1 g/cm3(Kuxelwe kwangaphambili)

ubushushu bokugcina:-20°C

pKa:2.18±0.40(Kuqikelelwe)

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Ukusetyenziswa

I-Pyrazolam

8-Bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine

Ubume

Isisombululo sePyrazolam

4H- [1,2,4] Triazolo[4,3-a] [1,4] benzodiazepine

I-8-bromo-1-methyl-6-(2-pyridinyl)-

I-8-Bromo-1-methyl-6- (2-pyridinyl) -4H- [1,2,4] triazolo [4,3-a] [1,4] ibe

nzodiazepine

Inkcazo

I-Pyrazolam (SH-I-04) yi-derivative ye-benzodiazepine ekuqaleni eyaphuhliswa liqela elikhokelwa nguLeo Sternbach eHoffman-La Roche kwi-1970s.

I-Pyrazolam inezakhiwo ezifanayo kwi-alprazolam kunye ne-bromazepam.Ngokungafaniyo nezinye i-benzodiazepines, i-pyrazolam ayibonakali ingena kwi-metabolism, endaweni yoko ikhutshwe ingatshintshi kumchamo.

Iipropati zeMichiza

I-Pyrazolam yi-benzodiazepine esetyenziswe kakubi ngokuzonwabisa.Njengezinye i-benzodiazepines, i-pyrazolam ineempembelelo ze-anxiolytic.

Usebenzisa I-Pyrazolam yi-benzodiazepine kunye nokupheliswa kwesiqingatha-ubomi malunga neeyure ze-17 kwaye akukho metabolites ebonakalayo kwi-serum yabantu kunye nomchamo;Ngaloo ndlela i-pyrazolam inokuhamba ingabonwa ngaphandle kobuchule bokuhlalutya kwezixhobo.

IsiceloI-Pyrazolam ngumyili we-benzodiazepine ethengiswe kwi-intanethi 'njengephezulu esemthethweni' okanye 'ikhemikhali yophando'.Ukusukela ekuveleni kwayo eYurophu kwiminyaka embalwa eyadlulayo, i-pyrazolam, kunye nezinye i-benzodiazepines zomyili, ziye zadibana nomsebenzi wetyala lophando.