2-Fluoroamphetamine INOMBOLO ye-CAS: 1716-60-5

I-2-fluamphetamine (2-FA) iyisidakamizwa esivuselelayo emndenini we-amphetamine futhi isithengiswe njengesidakamizwa esikhethekile.I-2-Fluoroamphetamine ihlukile ku-3- kanye no-4 -fluoroamphetamine endaweni yama-athomu e-fluorine iringi yephunga elimnandi, okuwenza abe ama-isomer ahambayo awodwa.Ukushintsha ama-athomu e-hydrogen ngama-athomu e-fluorine kwezinye izinhlanganisela ukuze kube lula ukudlula kwesithiyo segazi nobuchopho, njengoba kufiswa emithini yesimiso sezinzwa esimaphakathi, kuwumkhuba ovamile onikezwa yilokhu kushintshwa kwezibonelelo ngenxa yokwanda okuhambisanayo kwe-lipophilicity.

i-pharmacology
Umthamo we-anorexia (ukuvimbela okungu-50% kokudla kungakapheli amahora angu-2, kunikezwe ihora eli-1 kusengaphambili) = 15 mg/kg (amagundane; Oral).

I-analgesic dose (50% inhibition of tail-clip reaction) = 20 mg/kg (igundane; ip).

Umthelela kumfutho wegazi: 0.5 mg/kg (amagundane; I-Intravenous) ingakhuphula umfutho wegazi ngamamilimitha angu-29.