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99% Ilekun mimọ si Ilekun Ise Oogun Ite CAS 129954-34-3 Selank Peptide Lyophilized Powder Fun Itoju Arun Ẹdun

kukuru apejuwe:

Selank jẹ peptide meje pẹlu awọn abuda aibalẹ.
Selank, ti ​​ọna rẹ jẹ TKPRPGP, jẹ afọwọṣe sintetiki ti tuftsin-Tuftsin
Selank jẹ eroja ti o ni idagbasoke ni Institute of Molecular Genetics of the Russian Academy of Sciences.
Selank jẹ heptapeptide kan pẹlu ọna Thr-Lys-Pro Arg-Pro Gly-Pro (TKPRPGP).O jẹ afọwọṣe sintetiki ti tuftsin peptide Tuftsin eniyan.

Awọn afihan Iwadi:
1. O le ṣe atunṣe ikosile ti interleukin-6 (IL-6) ati ki o ni ipa lori iwọntunwọnsi ti awọn cytokines cell oluranlowo T.
2. O le ni ipa lori ifọkansi ti awọn neurotransmitters monoamine ati ki o fa iṣelọpọ ti serotonin.
3. O le ni kiakia mu ikosile ti ọpọlọ-ti ari neurotrophic ifosiwewe (BDNF) ni eku hippocampus.
Agbekalẹ: C33H57N11O9
Iwọn Molar: 751.887 g · mol


Alaye ọja

ọja Tags

Selank CAS 129954-34-3

Molikula C33H57N11O9

Molikula àdánù 751.887

Didara to peye 751.434

Selank Peptide CAS 129954-34-3 Iwadi

         Selank jẹ itọsẹ sintetiki ti tetrapeptide tuftsin ti o ni ilana proline-glycine-proline ni C-terminus ati pe o ni awọn iṣẹ anxiolytic ati egboogi-iredodo.O pọ si titobi ati oṣuwọn idasilẹ ti awọn ṣiṣan postsynaptic inhibitory ti awọn neuron ni agbegbe eku hippocampal CA1 nigba lilo ni ifọkansi ti 1 μM.O dinku ipele ti awọn idahun ti o ni ipa ati nọmba awọn igbiyanju ona abayo aṣiṣe ninu awọn eku ni ipo aapọn nla, mu ki awọn idahun iṣalaye-iwadii ti awọn eku pọ si ni ipo aimọ, ati dinku akoko awọn eku ti o lo ni aibikita ninu idanwo iwẹ fi agbara mu.O mu iṣẹ ṣiṣe locomotor ti Balb / c aibalẹ giga, ṣugbọn kii ṣe C57Bl / 6, awọn eku ni idanwo aaye ṣiṣi.Selank (0.01 mg/kg) dinku inaro ti a fa nipasẹ apomorphine ninu awọn eku.O tun dinku ikosile ti awọn Jiini ti o ni ibatan iredodo Il2rg ati Xcr1 ninu eegun asin lẹhin awọn iṣẹju 90 nigbati a nṣakoso ni iwọn lilo 100 μg/kg.

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