iphepha_ibhena

iimveliso

99% Umnyango ococekileyo ukuya emnyango weNkonzo yezoNyango iBanga le-CAS 129954-34-3 iSelank Peptide Lyophilized Powder yokuNyanga isifo seNeurological

inkcazelo emfutshane:

I-Selank yi-peptide esixhenxe eneempawu ezichasene nexhala.
USelank, olandelelwano lwakhe yi-TKPRPGP, yi-analogue eyenziweyo ye-tuftsin-Tuftsin
ISelank sisithako esiphuhliswe kwiZiko leMolekyuli yemfuza yeRussian Academy of Sciences.
I-Selank yi-heptapeptide ngokulandelelana kwe-Thr-Lys-Pro Arg-Pro Gly-Pro (TKPRPGP).Yi-analogue yokwenziwa ye-tuftsin peptide yabantu iTuftsin.

Imiboniso yoPhando:
1. Inokulawula ukubonakaliswa kwe-interleukin-6 (IL-6) kwaye ichaphazele ibhalansi ye-T helper cell cytokines.
2. Inokuchaphazela ukuxinwa kwe-monoamine neurotransmitters kwaye ibangele i-metabolism ye-serotonin.
3. Inokunyusa ngokukhawuleza ukubonakaliswa kwe-brain-derived neurotrophic factor (BDNF) kwi-rat hippocampus.
Ifomula: C33H57N11O9
Ubunzima beMolar: 751.887 g mol


Iinkcukacha zeMveliso

Iithegi zeMveliso

Selank CAS 129954-34-3

Imolekyuli yeC33H57N11O9

Ubunzima bemolekyuli 751.887

Umgangatho ochanekileyo 751.434

Selank Peptide CAS 129954-34-3 Uphando

         I-Selank yi-derivative derivative ye-tetrapeptide tuftsin equkethe i-proline-glycine-proline ulandelelwano kwi-C-terminus kwaye ine-anxiolytic and anti-inflammatory activities.Yandisa i-amplitude kunye nesantya sokukhupha i-postsynaptic currents ye-inhibitory ye-neurons kwindawo ye-rat hippocampal CA1 xa isetyenziswe kwi-concentration ye-1 μM.Iyanciphisa inqanaba leempendulo ezithintekayo kunye nenani leenzame eziphosakeleyo zokuphunyuka kwiigundane kwimeko yoxinzelelo olunzima, kwandisa iimpendulo ze-orientational-zophando lweegundane kwimeko engaqhelekanga, kwaye inciphisa ixesha leempuku ezichitha i-immobile kuvavanyo lokuqubha ngenkani.Yandisa umsebenzi we-locomotor we-high-anxiety Balb / c, kodwa kungekhona i-C57Bl / 6, iigundane kuvavanyo lwebala elivulekileyo.I-Selank (0.01 mg / kg) iyancipha i-verticalization eyenziwa yi-apomorphine kwiigundane.Kwakhona kunciphisa ukubonakaliswa kwejene ezinxulumene nokuvuvukala kwe-Il2rg kunye ne-Xcr1 kwi-spleen yegundane emva kwemizuzu ye-90 xa ilawulwa kwi-dose ye-100 μg / kg.

b82eb0a650f27f3c7ed3b0e15232bd37whatsapp

I-SERUM I-THYMIC FACTOR CAS 63958-90-7

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