China Intengiso eshushu CAS 623172-56-5 Palmitoyl Tripeptide-5
Ulwazi olusisiseko
Izithethantonye
(2S) -6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]hexanoic acid,2,2 ,2-trifluoroacetic acid
I-N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-L-lysine 2,2,2-trifluoroacetate (1:2)
I-Pal-KVK;palMitoyl tripeptide-5;
I-PalMtioyl Tripeptide-5;
I-SYN-COLL;Palmitoyl Tripeptide-5(Pal-KVK);
Palmitoyl tripeptide-5 bistrifluoracetate ityuwa
Ukusetyenziswa
IiPropati ezichasene nokuguga
I-Syn-Coll, okanye i-palmitoyl tripeptide-3/5 (i-Palmitoyl-lysyl-valyl-lysine bistrifluoracetate ityuwa), i-oligopeptide yesignali yokwenziwa eboniswe ukukhuthaza ukubunjwa kwe-collagen kwi-in vitro kunye nezifundo ze-vivo ngokusebenzisa i-TGFβ yokukhula.Indlela yale peptide ifana nomsebenzi we-thrombosponin I (TSPI).I-TSPI ibonakaliswa kwiiseli zedermal, ngakumbi ngexesha lokuphulukiswa kwesilonda.Le protheyini ibophelela kwi-TGFβ efihlakeleyo kwaye ibangela utshintsho oluhambelanayo, ukwandisa ukuveliswa kwe-collagen njengesiphumo esisezantsi.Olunye uphando lubonise ukuba unyango lwe-TSPI izilonda ze-null zegundane kunye ne-peptide KRFK yakwazi ukuhlangula ukusebenza kwe-TSP1 exhomekeke kwi-TGFβ kwiiseli zedermal.I-Syn-Coll iphuma kolu landelelwano oluye lwadityaniswa kwi-fatty acid moiety ukwenzela ukwanda kokungena.Kwiiseli ze-dermal fibroblast, iziphumo ze-pharmacologic ze-peptide ehambelanayo, i-KFK, kukunyusa i-collagen synthesis kunye nokunciphisa i-MMP-1 ibonakaliso nge-TGFβ.Ulingo olulawulwayo kumavolontiya angama-60 lubonise ukuba i-Syn-Coll yanciphisa ukuqina kwesikhumba kangcono kunezo zombini i-placebo kunye ne-Pal-KTTKS creams, xa isetyenziswe kabini imihla ngemihla kwiintsuku ze-84.
Inkcazo
I-Palmitoyl tripeptide-5 yi-peptide yokwenziwa kwaye iqulathe amatyathanga ama-3 e-amino acids adityaniswa kunye ne-fatty acids.I-Palmitoyl tripeptide inokungena kwi-epidermis kwaye inokungena nzulu kwi-dermis, apho inokunceda ukuvuselela imveliso ye-collagen kwaye inceda ukukhula kwezicubu eziphilileyo.
Inkcazo
I-Palmitoyl tripeptide-5 yi-cosmeceutical peptide.
Usebenzisa
I-Palmitoyl Tripeptide-5 yenziwe ngamatyathanga e-amino acids kwaye inokungena kwi-epidermis kwaye ingene nzulu kwidermis, apho inokunceda ukuvuselela imveliso ye-collagen kunye nokukhula kwezicubu ezinempilo.
Isicelo Palmitoyl Tripeptide-5 licandelo cell transduction, kwaye ikhuthaza imveliso collagen.Isetyenziswa ngokuqhelekileyo kwizithambiso zokuchasa ukuguga kunye nokuchasa imibimbi.
iinzuzo
IPalmitoyl Tripeptide-5 ilungisa kakhulu iipeptide ezininzi, iphucula ngokupheleleyo inkangeleko yolusu ngenxa yokwaluphala ukusuka ekukhuseleni ukuya ekusebenzeni kweseli ye-epidermis, i-basement membrane kunye ne-corium layer, amanqaku e-egstretch, amanqaku amaqhakuva kunye nescar ngenxa yelaser, njl njl. ukuguga okuhlala ixesha elide.Winkeypatented product in China.Idosi yayo ecetyiswayo yi-1 ~ 5%.
Indlela yokwenza
I-Palmitoyl tripeptide-5 isebenza kwi-skin receptors ethile kwaye ivuselela ukuveliswa kwe-collagen kwiiseli zethu zesikhumba.Iqinisa ulusu lwethu, inciphisa ukubonakala kwemibimbi kunye nemigca emihle.Yenza ulusu lwakho lubukeke lusempilweni kwaye lutsha.I-Palmitoyl Tripeptide-5 iphinda idibane ne-hyaluronic acid kunye nenkqubo yokuvelisa i-elastin.Isiphumo sokudibanisa sinyusa umthamo wamanzi, ukunciphisa ukushwabana kwesikhumba kunye nokuphucula ukuqina kwesikhumba.