Tuam Tshoj Kub Muag CAS 623172-56-5 Palmitoyl Tripeptide-5
Cov ntaub ntawv yooj yim
Synonyms
(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino] hexanoic acid, 2,2 , 2-trifluoroacetic acid
N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-L-lysine 2,2,2-trifluoroacetate (1:2)
Pal-KVK; palMitoyl tripeptide-5;
PalMtioyl Tripeptide-5;
SYN-COLL; Palmitoyl Tripeptide-5 (Pal-KVK);
Palmitoyl tripeptide-5 bistrifluoracetate ntsev
Kev siv
Anti-aging Properties
Syn-Coll, los yog palmitoyl tripeptide-3/5 (Palmitoyl-lysyl-valyl-lysine bistrifluoracetate ntsev), yog cov teeb liab hluavtaws oligopeptide uas tau pom los txhawb kev tsim collagen hauv ob qho tib si hauv vitro thiab hauv vivo kev tshawb fawb los ntawm kev loj hlob ntawm TGFβ.Cov txheej txheem ntawm peptide no zoo ib yam li thrombosponin I (TSPI) kev ua.TSPI tau qhia nyob rau hauv dermal hlwb, tshwj xeeb tshaj yog thaum lub qhov txhab kho.Cov protein no khi rau latent TGFβ thiab induces conformational hloov, ua rau zus tau tej cov collagen raws li ib tug downstream nyhuv.Ib txoj kev tshawb nrhiav pom tias kev kho mob ntawm TSPI null nas qhov txhab nrog peptide KRFK muaj peev xwm cawm tau TSP1-dependent activation ntawm TGFβ hauv dermal hlwb.Syn-Coll yog ib tug derivative ntawm no ib theem zuj zus uas tau ua ke mus rau ib tug fatty acid moiety rau nce permeation.Nyob rau hauv dermal fibroblast hlwb, cov tshuaj pharmacological ntawm ib tug muaj feem xyuam peptide, KFK, yog kom collagen synthesis thiab downregulate MMP-1 qhia los ntawm TGFβ.Kev tswj xyuas ntawm 60 tus neeg tuaj yeem pab dawb tau pom tias Syn-Coll txo cov tawv nqaij roughness zoo dua li cov placebo thiab Pal-KTTKS cream, thaum siv ob zaug ib hnub rau 84 hnub.
Kev piav qhia
Palmitoyl tripeptide-5 yog ib qho hluavtaws peptide thiab muaj 3 chains ntawm amino acids txuas ua ke nrog fatty acids.Palmitoyl tripeptide tuaj yeem nkag mus rau hauv epidermis thiab tuaj yeem nkag mus tob rau hauv cov dermis, qhov uas nws tuaj yeem pab txhawb kev tsim cov collagen thiab pab kom cov nqaij mos loj hlob zoo.
Kev piav qhia
Palmitoyl tripeptide-5 yog cosmetic peptide.
Siv
Palmitoyl Tripeptide-5 yog tsim los ntawm cov saw hlau ntawm cov amino acids thiab tuaj yeem nkag mus rau hauv cov epidermis thiab nkag mus tob rau hauv cov tawv nqaij, qhov twg tuaj yeem pab txhawb kev tsim cov collagen thiab kev noj qab haus huv cov ntaub so ntswg.
Daim ntawv thov Palmitoyl Tripeptide-5 yog ib feem ntawm kev hloov ntawm tes, thiab txhawb kev tsim cov collagen.Nws yog feem ntau siv nyob rau hauv anti-aging thiab anti-wrinkle tshuaj pleev ib ce.
cov txiaj ntsig
Palmitoyl Tripeptide-5 yog super kho ntau-peptide, ua kom pom tseeb ntawm daim tawv nqaij vim kev laus los ntawm kev tiv thaiv kev ua kom cov cell ntawm epidermis, hauv qab daus membrane thiab corium txheej, egstretch marks, pob txuv thiab pob txuv vim laser, thiab lwm yam. Txhim kho firmness, sofeness thiab elasticity ntawm daim tawv nqaij, ntev tin-aging.Winkeypatented khoom nyob rau hauv Suav teb.Nws pom zoo npaum li cas yog 1 ~ 5%.
Mechanism ntawm kev ua
Palmitoyl tripeptide-5 ua rau cov tawv nqaij tshwj xeeb receptors thiab txhawb kev tsim cov collagen hauv peb cov tawv nqaij.Nws firms peb cov tawv nqaij, txo cov tsos ntawm wrinkles thiab nplua-lines.Nws ua rau koj cov tawv nqaij zoo dua qub thiab tshiab.Palmitoyl Tripeptide-5 kuj cuam tshuam nrog hyaluronic acid thiab elastin ntau lawm system.Cov nyhuv sib xyaw ua ke yog cov dej ntau ntxiv, txo qhov wrinkling ntawm daim tawv nqaij thiab txhim kho cov tawv nqaij firmness.