Izithako ezisebenzayo zoXhomezo lweSteroids Sarms CAS 595-33-5 Megestrol acetate
Wickr/Telegram : Daisey521
Whatsapp : 008618034511316
Skype: live:.cid.93f1bd48473d87a8
Email: saleroom@yeah.net
Ulwazi olusisiseko
I-Acetate yeMegestrolluhlobo lwetyuwa ye-acetate ye-megestrol, i-synthetic derivative ye-progesterone ye-hormone yesini eyenzeka ngokwemvelo ene-anti-estrogenic kunye nomsebenzi we-antineoplastic.
Isetyenziswa rhoqo kunyango lwezigulane ezinomdlavuza webele we-metastatic.Ngokuqhelekileyo kunyanyezelwe kakuhle, ngaphandle kokuba kunokubangela ubunzima obungafunekiyo.Emva koko, kwaboniswa ukuba i-megestrol acetate ivelise ubunzima kwiintlobo ezahlukeneyo zezigulane zomhlaza we-cachectic.
Ukunciphisa okubalulekileyo amanqanaba e-inserum ye-IL-1a kunye ne-b, i-IL-2, i-IL-6, kunye ne-TNF-o yabonwa kwizigulane zomhlaza eziphathwe nge-megestrol acetate enokuthi ithwale kwindlela yokuphucula ukutya kunye nokuzuza ubunzima bomzimba. ukuba isiphumo, ubuncinci ngokuyinxenye, silawulwa yi-NPY, isivuseleli esinamandla sokutya.
Ukusetyenziswa
1. I-Megestrol acetate USP (Megace)isetyenziselwa ukunyanga iCarcinoma yebele okanye endorometrium.
2. I-acetate yeMegestrol (Megace), i-semi-synthetic progestational steroid, yeyona nto isebenzayo eyaziwayo evuselela umdla ngoku.Ngaphambili isetyenziswe kwizigulane ezinomhlaza kunye nokufumana i-immunodeficiency syndrome, kuphela izifundo ezimbalwa eziye zaqwalasela ukusetyenziswa kweli chiza kubantu abadala abangondlekanga.
I-Megestrol acetate iluncedo ukuba i-anorexia enzulu yimbonakaliso ephambili ye-cachexia kwaye ukuba kulindeleke ukuba ukusinda kwiiveki ukuya kwiinyanga.I-Megace ibonakaliswe ukwandisa kakhulu ukutya, kodwa kungekhona ukusinda.Kwizigulane ezinobomi obufutshane obuqikelelweyo, ikhosi emfutshane ye-corticosteroids ingaba luncedo ekuvuseleleni ukutya kwaye ibe nemiphumo emihle kwi-nausea, intlungu kunye ne-asthenia.
Inkcazo ngokubanzi
I-17-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate(i-Megace), i-progestin esetyenziswa ngokuyinhloko kulawulo lwe-palliative ye-recurrent, engasebenziyo, okanye i-metastatic endometrialor breast carcinoma.I-acetate ye-Megestrol nayo ibonakaliswe ekuphuculeni ukutya kwizigulane ezine-AIDS.Isiseko se-biochemical kolu kusetyenziswa kwe-megestrol ayicacanga.
Ukusetyenziswa kweKlinikhiUmsebenzi weProgestin uphuculwa ngakumbi xa i-double bond iqaliswa phakathi kwezikhundla ze-6 kunye ne-7, njengoko ifumaneka kwi-acetate ye-megestrol.I-Megestrol isetyenziselwa ikakhulu kunyango lwe-carcinomas yebele kunye ne-endometrial kunye nabasetyhini be-postmenopausal abane-carcinoma exhomekeke kwi-hormone.
Inkangeleko yoKhuselekoI-carcinogen erhanelwayo kunye nedatha yovavanyo lwe-carcinogenic kunye ne-teratogenic.Ityhefu ngokufakwa emithanjeni.Iziphumo zokuzala kwabantu nge-bp kunye neendlela zokufakelwa: iimpembelelo kwi-ovari kunye ne-fallopian tubes, utshintsho lokuya esikhathini, kunye nokutshintsha kwesalathisi sokuzala.Idatha yokuguqulwa kwengxelo.Iziphumo zovavanyo lokuzala.Xa ishushu ukuze ibole ikhupha umsi omuncu kunye nomsi ocaphukisayo.Ichiza elisemthethweni le-FDA elisetyenziselwa ukunyanga i-endometriosis kunye nomhlaza wamabele.I-steroid.