Ongeza Ukuaji wa Misuli Daraja la Pharma Poda LGD-4033 CAS 1165910-22-4
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Matumizi
LGD-4033 ni moduli isiyo ya steroidal ya mdomo, ya kuchagua androgen receptor katika vijana wenye afya.
Ligandrol (LGD-4033, VK-5211) ni aina mpya ya steroid bure na simulizi teule receptor kidhibiti na mshikamano wa juu (Kd ni kuhusu 1 nM) na high selectivity kwa androgen receptor.
Katika mifano ya wanyama, LGD-4033 ina shughuli za anabolic katika misuli, kizuizi cha kunyonya na shughuli za anabolic katika mfupa, na kuchagua kwa misuli ni kubwa zaidi kuliko ile ya zamani ya Chemicalbook gland.Katika mkusanyiko uliogunduliwa, LGD-4033 ni salama na imevumiliwa vizuri.Uondoaji wake wa nusu ya maisha ni ya muda mrefu, kuhusu masaa 24-36, inaonyesha sifa za pharmacokinetic za mstari.
Vipimo
| Jina la bidhaa: | LGD-4033 |
| CAS: | 1165910-22-4 |
| MF: | C14H12F6N2O |
| MW: | 338.25 |
| Kiwango cha kuyeyuka | 108 - 111°C |
| Kuchemka | 439.9±45.0 °C(Iliyotabiriwa) |
| msongamano | 1.45±0.1 g/cm3(Iliyotabiriwa) |
| joto la kuhifadhi. | Hygroscopic, -20°C Friji, Chini ya angahewa ajizi |
| umumunyifu | Asetoni (Kidogo), Chloroform (Kidogo, Moto), Methanoli (Kidogo) |
| pka | 12.06±0.20(Iliyotabiriwa) |
| fomu | Imara ya fuwele |
| rangi | Nyeupe hadi Beige Pale |
| Utulivu | Hygroscopic |
Sinonimia:
1. 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile(LGD-4033);LGD-4033
2. 4-[(2R)-2-[(1R)-2,2,2-Trifluoro-1-hydroxyethyl]-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrile
3. 4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-trifluoroMethyl)benzonitrile
4. LIGANDROL
5. 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
6. lgd 4033 sarms poda lgd-4033 ligandrol
7. PODA LGD-4033 LIGANDROL
8. CAS 1165910-22-4
