2-Fluoroamphetamine CAS NO :1716-60-5

2-fluamphetamine (2-FA) mushonga unokurudzira mumhuri yeamphetamine uye wakatengeswa semushonga unokosha.2-Fluoroamphetamine inosiyana kubva pa 3- na 4 -fluoroamphetamine iri panzvimbo yemaatomu efluorine paringi inonhuhwirira, zvichiita kuti ive maisomer ekumisikidzana.Kutsiva maatomu ehaidhirojeni nemaatomu efluorine mune mamwe macompounds kufambisa nzira yeropa-brain barrier, sezvinodiwa kune central nervous system drug, itsika yakajairika inopihwa nekutsiviwa kwezvipo nekuda kwekuwedzera kunoenderana kwe lipophilicity.

pharmacology
Anorexia dose (50% inhibition yekudya kwekudya mukati maawa maviri, yakapiwa 1 awa nguva isati yasvika) = 15 mg / kg (makonzo; Oral).

Analgesic dose (50% inhibition yemuswe-clip reaction) = 20 mg/kg (mouse; ip).

Mhedzisiro paBP: 0.5 mg/kg (makonzo; Intravenous) inogona kusimudza BP ne29 millimeters.