2-Fluoroamphetamine CAS NO: 1716-60-5

2-fluamphetamine (2-FA) ndi mankhwala olimbikitsa m'banja la amphetamine ndipo agulitsidwa ngati mankhwala apadera.2-Fluoroamphetamine imasiyana ndi 3- ndi 4 -fluoroamphetamine m'malo mwa maatomu a fluorine pa mphete yonunkhira, kuwapanga kukhala ma isomers okhazikika a wina ndi mnzake.Kusintha maatomu a haidrojeni ndi maatomu a fluorine m'magulu ena kuti apititse patsogolo ndime ya chotchinga cha magazi-ubongo, monga momwe amafunira mankhwala osokoneza bongo apakati, ndizofala zomwe zimaperekedwa ndi kulowetsedwa kwa ndalama izi chifukwa cha kuwonjezeka kwa lipophilicity.

pharmacology
Mlingo wa anorexia (50% kuletsa kudya mkati mwa maola 2, kupatsidwa 1 ola pasadakhale) = 15 mg/kg ( makoswe; Oral).

Mlingo wa analgesic (50% inhibition of tail-clip reaction) = 20 mg/kg (mbewa; ip).

Zotsatira za kuthamanga kwa magazi: 0.5 mg/kg (makoswe; Mtsempha) amatha kukweza kuthamanga kwa magazi ndi 29 millimeters.