Dịkwuo Akwara Too Pharma ntụ ntụ ntụ ntụ LGD-4033 CAS 1165910-22-4
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Ojiji
LGD-4033 bụ onye na-abụghị steroidal ọnụ, nhọrọ androgen receptor modulator na ndị na-eto eto nwere ahụike.
Ligandrol (LGD-4033, VK-5211) bụ ụdị ọhụrụ nke steroid free na ọnụ na-ahọrọ androgen receptor regulator nwere nnukwu mmekọrịta (Kd bụ ihe dịka 1 nM) na nhọrọ dị elu na onye na-anabata androgen.
N'ụdị anụmanụ, LGD-4033 nwere ọrụ anabolic na akwara, mgbochi nke absorption na ọrụ anabolic na ọkpụkpụ, na nhọrọ nke anụ ahụ dị elu karịa nke dị na mbụ Chemicalbook gland.N'ebe nleba anya achọpụtara, LGD-4033 dị mma yana nke ọma.Ọkara ndụ mkpochapụ ya dị ogologo, ihe dị ka awa 24-36, na-egosi njirimara pharmacokinetic linear.
Nkọwapụta
| Aha ngwaahịa: | LGD-4033 |
| CAS: | 1165910-22-4 |
| MF: | C14H12F6N2O |
| MW: | 338.25 |
| Ebe mgbaze | 108-111 Celsius C |
| Ebe esi nri | 439.9± 45.0 Celsius C(buru amụma) |
| njupụta | 1.45±0.1 g/cm3 (buru amụma) |
| nchekwa okpomọkụ. | Hygroscopic, -20 Celsius C friza, N'okpuru ikuku inert |
| solubility | Acetone (obere), Chloroform (obere, ekpo ọkụ), methanol (obere) |
| pka | 12.06± 0.20 (buru amụma) |
| ụdị | Igwe kristal siri ike |
| agba | Ọcha na-acha aja aja |
| Nkwụsi ike | Hygroscopic |
Oyiri:
1. 4-((R) -2-((R) -2,2,2-trifluoro-1-hydroxyethyl) pyrrolidin-1-yl) -2-trifluoroMethyl) benzonitrile (LGD-4033); LGD-4033
2. 4-[(2R) -2-[(1R) -2,2,2-Trifluoro-1-hydroxyethyl] -1-pyrrolidinyl] -2- (trifluoromethyl) benzonitrile
3. 4-((R) -2-((R) -2,2,2-Trifluoro-1-hydroxyethyl) pyrrolidin-1-yl) -2-trifluoroMethyl) benzonitrile
4. LIGANDROL
5. 4-[(2R) -2-[(1R) -2,2,2-trifluoro-1-hydroxyethyl] pyrrolidin-1-yl] -2- (trifluoromethyl) benzonitrile
6. lgd 4033 sarms ntụ ntụ lgd-4033 ligandrol
7. Ntụ ntụ LGD-4033 LIGANDROL
8. CAS 1165910-22-4
