2-Fluoramphetamine CAS NO ：1716-60-5

ʻO ka 2-fluamphetamine (2-FA) he lāʻau hoʻoikaika i ka ʻohana amphetamine a ua kūʻai ʻia ma ke ʻano he lāʻau lapaʻau kūikawā.'Oko'a ka 2-Fluoroamphetamine mai ka 3- a me ka 4-fluoroamphetamine i ke kūlana o nā ʻātoma fluorine ma ke apo ʻala, e hoʻolilo iā lākou i nā isomer kūlana o kekahi i kekahi.ʻO ka hoʻololi ʻana i nā ʻātoma hydrogen me nā ʻātoma fluorine i loko o kekahi mau pūhui e hoʻomaʻamaʻa i ka hele ʻana o ka pale koko-lolo, e like me ka makemake no nā lāʻau lapaʻau o ke kikowaena, he hana maʻamau i hāʻawi ʻia e kēia hoʻololi ʻana i nā haʻawina ma muli o ka piʻi like ʻana o ka lipophilicity.

lāʻau lapaʻau
Anorexia dose (50% inhibition o ka meaʻai i loko o 2 hola, hāʻawi ʻia 1 hola ma mua) = 15 mg/kg (ʻiole; Oral).

Analgesic dose (50% inhibition of tail-clip reaction) = 20 mg/kg (iole; ip).

Ka hopena i ke koko: 0.5 mg/kg (nā ʻiole; Intravenous) hiki ke hoʻonui i ke koko e 29 millimeters.