Dan Adam Choroinic Gonadotrophin HCG CAS: 9002-61-3

Human chorionic gonadotropin (hCG) wani hormone ne na glycoprotein da ke ɓoye ta sel endodermal na placental.Babban aikinsa shi ne tada hankalin corpus luteum, wanda ke da tasiri ga ci gaba da fitar da estrogen da progesterone, don inganta samuwar mahaifa da kuma sa mahaifa ya girma da girma.Da zarar an dasa amfrayo, ƙwayoyin blastoderm sun fara ɓoye hCG, don haka ana iya ƙayyade ciki ta hanyar matakan hCG a cikin jini ko fitsari.

Ya ƙunshi ragowar amino acid 244, tare da nauyin kwayoyin halitta na 36.7kDa da girman 7.5 × 3.5 × 3 nm.Yana da heterodimer tare da nau'in α guda ɗaya kamar luteinizing hormone (LH), hormone-stimulating hormone (FSH) da thyrotropin (TSH), amma daban-daban β subunit.Subunit na α ya ƙunshi ragowar amino acid guda 92, kuma sashin β ya ƙunshi ragowar amino acid guda 145.

Haɗin hCG a cikin mata yana ƙaruwa sosai bayan ɗaukar ciki, kuma kasancewar hCG a cikin jini da fitsari yana ɗaya daga cikin alamun farko na ciki kuma ana amfani dashi don gwajin ciki.

(1) Yana da aikin FSH da LH don kula da tsawon rayuwar corpus luteum da kuma sanya corpus luteum ya zama corpus luteum;

(2) Haɓaka aromatization na androgens zuwa estrogen, da kuma tada samuwar progesterone;

(3) Hana tasirin motsa jiki na lectin shuka akan lymphocytes, ana iya sanya gonadotropin chorionic gonadotropin a saman sel trophoblast, don guje wa harin ƙwayoyin trophoblast na mahaifa ta hanyar lymphocytes na uwa;

(4) Ayyukan LH, kafin tayin tayi ya ɓoye LH, yana ƙarfafa gwajin tayi don ɓoye testosterone don inganta bambancin jima'i na namiji;Hakanan zai iya haɓaka haɓakar gonadal, namiji na iya tada kuzarin sel na testis mesenchymal, ƙara haɓakar ƙwayar hormone namiji (testosterone).Yana da matukar muhimmanci ga kula da maza marasa lafiya da pituitary hadin gwiwa lahani, wanda ba zai iya kawai inganta gonad ci gaban da namiji hormone secretion, amma kuma inganta ci gaban na biyu jima'i halaye.

(5) Yana iya ɗaure ga mai karɓar TSH na ƙwayoyin thyroid na mahaifa kuma yana motsa ayyukan thyroid.