I-China ihlinzeka nge-Lidocaine CAS 137-58-6 Ngenani Elingcono Kakhulu
Ulwazi Oluyisisekelo
Incibilika ku-ethanol, ether, benzene, chloroform namafutha, engancibiliki emanzini.I-base hydrochloride evame ukusetshenziswa, i-lidocaine hydrochloride (C14H22N2O·HCL, [73-78-9]) i-powder emhlophe e-crystalline.Iphuzu elincibilikayo lingu-127-129 ℃, kanti indawo encibilikayo ye-monohydrate ingu-77-78℃.Incibilika kakhulu emanzini, 0.5% enamanzi pHO4.0-5.5.Ukunambitheka kwe-hemp okubabayo nokungenaphunga.
Ukusetshenziswa
Umkhiqizo uyisibulali-zinzwa sendawo se-amide.Isetshenziswa kabanzi ku-anesthesia yendawo, i-infiltration anesthesia, i-anesthesia yokuqhuba kanye ne-epidural anesthesia.I-LD50 ye-lidocaine hydrochloride yayingu-290mg/kg.
Izicelo zomtholampilo zifaka izibulala-zinzwa zokungenwa, i-epidURAL anesthesia, i-anesthesia yendawo (kuhlanganise ne-mucosal anesthesia ngesikhathi se-thoracoscopy noma ukuhlinzwa kwesisu), kanye ne-nerve block.I-epinephrine ingangezwa ku-anesthetic ukuze kwandiswe isikhathi sokubulala izinzwa futhi kuncishiswe imiphumela engemihle njengobuthi nge-lidocaine.
I-Lidocaine ingabuye isetshenziselwe ukwelapha i-ventricular arrhythmias ngemva kwe-acute myocardial infarction, okuhlanganisa ukufinyela kwe-ventricular ngaphambi kwesikhathi, i-ventricular tachycardia, i-ventricular arrhythmias ebangelwa ubuthi be-digitalis, ukuhlinzwa kwenhliziyo kanye ne-catheterization ye-cardiac, kuhlanganise ne-ventricular premature contractions, i-ventricular tachycardia kanye ne-ventricular tachycardia.Ibuye isetshenziswe ezigulini ezinesimo se-epilepticus ezingaphenduli kwamanye ama-anticonvulsants kanye ne-anesthesia yendawo noma ye-intraspinal.Ngokuvamile ayisebenzi ngokumelene ne-supraventricular arrhythmias.
Imininingwane
| Igama Lomkhiqizo | I-Lidocaine |
| I-CAS | 137-58-6 |
| MF | I-C14H22N2O |
| MW | 234.34 |
| EINECS | 205-302-8 |
| Iphoyinti lokuncibilika | 66-69°C |
| Iphuzu elibilayo | bp4 180-182°;bp2 159-160° |
| ukuminyana | 0.9944 (isilinganiso esinzima) |
| inkomba ye-refractive | 1.5110 (isilinganiso) |
| Fp | 9℃ |
| izinga lokushisa lokugcina. | Gcina kwa-RT |
| ukuncibilika | i-ethanol: 4 mg/mL |
| pka | pKa 7.88(H2O)(Cishe) |
| ifomu | impushana |
| umbala | Okumhlophe kuya kokuphuzi kancane |
| Ukuncibilika kwamanzi | cishe engancibiliki |
| I-Merck | 14,5482 |
| Ukuzinza: | Izinzile.Akuhambisani nama-oxidizing agents aqinile. |
| I-InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| Ireferensi ye-CAS Database | 137-58-6(CAS DataBase Reference) |