I-Arhente yoThengiso eHotyo yokuLungisa iArhente iPhucula ukusebenza kweNtliziyo i-Thymosin β-4 CAS 77591-33-4 Thymosin beta 4 acetate powder powder

UThengiso olushushu lwe-Arhente yoLungiso lwemeko luPhucula uMsebenzi weNtliziyo i-Thymosin β-4 CAS 77591-33-4 Thymosin beta 4 iacetate yomgubo oMhlophe umfanekiso oFakelweyo

inkcazelo emfutshane:

Igama eliqhelekileyo:I-Thymosin β-4

Inombolo yeCAS:77591-33-4

Ifomula yemolekyuli:I-C212H350N56O78S

Ubunzima bemolekyuli:4963.4408

Umqulu:Ibhotile,Ibhegi,Ibhokisi,iGubu

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Uphawu:

Igama eliqhelekileyo	Thymosin beta 4	Igama lesiNgesi	Thymosin beta 4 acetate
Inombolo yeCAS	77591-33-4

Ifomula yemolekyuli	C212H350N56O78S
Ubunzima bemolekyuli	4963.44000
Ubunzima obuchanekileyo	4960.49000
PSA	2245.98000

Ukusetyenziswa:

I-Thymosin β-4 yi-endogenous pro-angiogenic, i-fibroblast-activating peptide ebandakanyeka kulawulo lwehomoni.I-Thymosin β-4 ikwabonisa imisebenzi ye-immunomodulatory kunye ne-cardioprotective.I-Thymosin β-4 iphucula iya kuphiliswa kumcimbi wentliziyo kwaye iphucule umsebenzi wentliziyo kwi-vivo.I-Thymosin i-β-4 idibanisa i-G-actin filaments, ikhusela i-actin polymerization.

I-Thymosin Beta-4 yi-43-amino-acid peptide ekhuthaza ukuphilisa kuwo wonke umzimba.Kwakhona ineempawu ezichasayo.Ifunyenwe ngokwemvelo kwiindawo eziphakamileyo zokulimala, iprotheni enyibilikayo yamanzi inokulungisa umonakalo wezicubu kunye nokulawula ukufuduka kweeseli kwindawo.Inokuphucula ukuphulukiswa kwesilonda kunye nokulungiswa kwesikhumba kuphela, kodwa kunye nengqondo, intambo yomgogodla kunye nentliziyo.Iingcali zonyango zithatha i-Thymosin Beta-4 njengento ekhuselekileyo nenamandla kwindlela yayo yendalo okanye yokwenziwa eyaziwa ngokuba yi-TB-500.
Ukongeza, i-TB4 inobunzima obuphantsi bemolekyuli kwaye ayibopheleli kwi-extracellular matrix.Oku kwenza kube lula ukuhamba kuzo zonke izihlunu zomzimba, ezikhuthaza ukukhawuleza kokuphiliswa.I-peptide ihamba imigama emide, ngoko ayisoloko itofwa ngokuthe ngqo kwindawo yokwenzakala.Ngelixa abanye bakholelwa ukuba ukuyitofa kufutshane nendawo eyenzakeleyo kuvelisa iziphumo ezingcono, ubungqina bekliniki bubonisa ngenye indlela.