GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide

I-Pralmorelin (INN) (igama lokuthengisa i-GHRP Kaken 100; Amagama ekhowudi yophuhliso lwangaphambili i-KP-102, i-GPA-748, i-WAY-GPA-748), eyaziwa ngokuba yi-pralmorelin hydrochloride (JAN) kunye ne-pralmorelin dihydrochloride (USAN), kwaye ngokukodwa, Ukukhula I-hormone ekhupha i-Peptide 2 (GHRP-2), i-hormone yokukhula secretagotor (GHS), isetyenziswe njenge-arhente yokuxilonga kwaye ithengiswe kwifom yokuqulunqa idosi enye yi-Kaken Pharmaceutical yaseJapan yokuvavanya ukusilela kwe-hormone yokukhula (GHD).

I-Pralmorelin yi-synthetic peptide drug kunye nomsebenzi womlomo.Ngokukodwa, i-analogue ye-methoxyenkephalin kunye nokulandelelana kwe-amino acid D-Ala-D - (β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Isebenza njenge-auxin ekhupha i-peptide / i-hormone yokukhula i-secretin receptor ( GHSR) i-agonist kwaye lichiza lokuqala lolo hlobo ukuba lingeniswe ekliniki.Ulawulo olululo lwechiza lonyusa kakhulu amanqanaba e-plasma ye-hormone yokukhula (GH) kwaye ikhuthaza indlala ngokuthembekileyo kwaye inyuse ukutya ebantwini.

I-Pralmorelin ikwafundelwa i-GHD kunye nesiqu esifutshane (i-pituitary dwarfism) kwaye yangena kwisigaba sesi-II solingo lwezonyango kwezi zalathiso, kodwa ekugqibeleni ayizange ifikelele kwintengiso.Oku kungenxa yokuba amandla epramoline okunyusa amanqanaba eplasma GH asezantsi kakhulu kwizigulane ze-GHD kunabantu abasempilweni.