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High Purity Pharma API CAS14769-73-4 Hydrochloride Levamisole Base

tlhaloso e khuts'oane:


  • Lebitso le tloaelehileng:Levamisole
  • Nomoro ea CAS:14769-73-4
  • MF:C11H12N2S
  • MW:204.29
  • EINECS:238-836-5
  • Sebaka sa ho qhibiliha:60-61,5 °
  • alpha:D25 -85.1° (c = 10 ka chloroform)
  • Sebaka se belang:344.4±45.0 °C(E boletsoeng esale pele)
  • density :1.32±0.1 g/cm3(E boletsoeng esale pele)
  • mocheso oa polokelo.:E tiisitsoe sebakeng se omileng, 2-8 ° C
  • pka:10.00±0.40(E boletsoeng esale pele)
  • Sephutheloana:Mokotla, Lebokose
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    Litaba tsa Motheo

    CAS14769-73-4 Hydrochloride Levamisole Base

    Tlhaloso

    A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole e nang le S configuration.E sebelisoa (ka kakaretso e le letsoai la monohydrochloride) ho phekola tšoaetso ea seboko sa likokoana-hloko likolobe, linku le likhomo 'me e kile ea sebelisoa ho huma e le motlatsi oa chemotherapy bakeng sa phekolo ea mefuta e fapaneng ea kankere.E boetse e sebelisoa haholo joalo ka sehlaseli sa coccaine.

    Lipontšo

    Levamisole (Ergamisol) ke lithethefatsi tse thibelang likokoana-hloko tse fumanoeng ho ntlafatsa ts'ebetso ea T-cell le ho itšireletsa mafung.Moriana o ntlafatsa bophelo ba bakuli ba nang le kankere ea colorectal e tsosolositsoeng ha e kopantsoe le 5-fluorouracil;mochine oa tšebelisano ena ha o tsejoe.Levamisole ha e na ts'ebetso ea antitumor khahlano le mofets'e o thehiloeng kapa oa metastatic mme ha e so fumanehe e le molemo kalafong ea adjuvant ea mofets'e ntle le mofets'e oa colorectal.

    Litlamorao tse kholo tsa levamisole ke ho nyekeloa ke pelo le anorexia.Ho 'nile ha hlokomeloa lekhopho la letlalo, ho hlohlona, ​​matšoao a kang a ntaramane le feberu.

    Lipontšo

    Levamisole (Ergamisol) qalong e ile ea etsoa e le moriana oa antihelminthic.E matlafatsa litlamorao tsa li-antigens, mitogens, lymphokines, le chemotactic factor lymphocytes, granulocytes le macrophages.Ho bontšitsoe ho eketsa ts'ireletso ea lisele tsa T cell.

    Levamisole e 'nile ea sebelisoa ka katleho ho phekola mafu a sa foleng.E boetse e amohetsoe hore e sebelisoe hammoho le fluorouracil kalafong ea mofetše oa colorectal.

    CAS 94-15-5
    Levamisole
    Levamisole

    Tšebeliso

    Lisebelisoa Phetoho ea karabo ea baeloji.

    Lisebelisoa   Levamisole e sebelisoa bakeng sa maemo a pele le a bobeli a immunodeficient, mafu a autoimmune, mafu a sa foleng le a khutlang, adenocarcinoma ea mala a maholo, helmintosis, le ramatiki ea ramatiki.Litlhaloso tse tšoanang tsa moriana ona ke decaris, tetramizole le tse ling.

    Levimasole hape ke sethethefatsi sa khetho bakeng sa ascardiasis.Liphuputso tse ngata li bontša hore tekanyo e le 'ngoe ea levamisole e folisa ho tloha ho 90 ho isa ho 100% ea bakuli ba nang le ascardiasis, haholo-holo ba nang le A. duodenale.Ha e sebetse hantle khahlanong le ancylostomiasis le strongyloidiasis.Leha ho le joalo, ha e sebetse khahlanong le N. americanus.Ho bonahala eka e na le phello ea gangliostimulating ho lisele tsa likokoana-hloko libakeng tsa parasympathetic le tse nang le kutloelo-bohloko.Ho feta moo, ho nahanoa hore sethethefatsi sena se na le phello ea immunomodulatory ho 'mele oa moeti.Litlhaloso tse tšoanang tsa lithethefatsi tsena ke decaris, solacil, ergamisol, tramisol, immunol, le tse ling.

    Tšebeliso ea Clinical

    Tšoaetso ea Ascariasis Hookworm

    Levamisole e sebelisitsoe ho ramatiki ea ramatiki le maemo a mang ao ho thoeng a arabela tšebetsong ea ona ea ho itšireletsa mafung.

    Mosebetsi oa Phekolo

    Antiinflammatory

    Mosebetsi oa likokoana-hloko

    Mosebetsi oa eona o ka sehloohong o khahlano le Asc.li-lumbricoides le li-hookworms.Liboko lia holofala ’me li fetisoa ka mantleng ka mor’a lihora tse seng kae.

    Lisebelisoa tsa Meriana

    L-isomer ea tetramisole, e fumanehang e le monohydrochloride.D-isomer ha e na tšebetso ea anthelmintic.E qhibiliha haholo metsing 'me e tsitsitse sebakeng se omileng.

    Mokhoa oa ts'ebetso

    Levamisole e na le ts'ebetso ea immunomodulating.Ho lumeloa hore e laola mekhoa ea lisele tsa tsamaiso ea 'mele ea ho itšireletsa mafung,' me mokhoa oa ts'ebetso ea eona o ka amahanngoa le ts'ebetso le kholo e ntseng e eketseha ea T-lymphocyte, palo e eketsehileng ea monocyte le ts'ebetso ea macrophages, hammoho le ts'ebetso e eketsehileng le hemotaxis ea neutrophylic. li-granulocyte.Levamisole e boetse e bonts'a ketso ea anthelmin.E boetse e eketsa matla a 'mele a ho hanyetsa ka kakaretso le ho tsosolosa ts'ebetso e fetotsoeng ea T-lymphocyte le phagocyte.E ka boela ea phethahatsa ts'ebetso ea immunomodulatory ka ho matlafatsa karabelo e fokolang ea ts'ireletso ea lisele, ho fokolisa karabelo e matla, le ho se be le phello ho karabelo e tloaelehileng.


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