GHRP-2/Pralmorelin CAS:158861-67-7 d-ala-β- (2-naphthyl) -d-ala-trp-d-phe-lys amide

Pralmorelin (INN) (magaca ganacsiga GHRP Kaken 100; Magacyada koodhka hore ee horumarinta KP-102, GPA-748, WAY-GPA-748), oo sidoo kale loo yaqaan pralmorelin hydrochloride (JAN) iyo pralmorelin dihydrochloride (USAN), iyo gaar ahaan, Kobaca hoormoonka sii daaya Peptide 2 (GHRP-2), xoghaynta hoormoonka koritaanka (GHS), waxaa loo isticmaalaa sidii wakiilka ogaanshaha waxaana lagu suuq geeyaa qaab hal-door ah oo ay bixiso Kaken Pharmaceutical ee Japan si loo qiimeeyo yaraanta hormoonka koritaanka (GHD).

Pralmorelin waa daawada peptide synthetic oo leh dhaqdhaqaaq afka ah.Gaar ahaan, waa analoog ah methoxyenkephalin oo leh taxanaha amino acid D-Ala-D -(β-naphthyl) -ala-trp-d-phe-Lys-NH 2. Waxay u shaqeysaa sidii auxin sii deynaya peptide / hormoonka koritaanka ee soo-dhoweynta (hormoonka koritaanka) GHSR) agonist waana dawadii ugu horaysay ee nooceeda ah ee la soo geliyo rugta caafimaadka.Maamulka degdega ah ee daawadu waxay si weyn u kordhisaa heerarka hoormoonka koritaanka plasma (GH) waxayna si la isku halleyn karo u kicisaa gaajada waxayna kordhisaa qaadashada cuntada ee bini'aadamka.

Pralmorelin waxaa sidoo kale lagu baranayaa GHD iyo dhererka gaaban (pituitary dwarfism) oo galay marxaladda II ee tijaabooyinka bukaan-socodka ee calaamadahan, laakiin ugu dambeyntii waligiis uma dhigin suuqa.Tani waxay noqon kartaa sababtoo ah awoodda pramoline ee kordhinta heerarka plasma GH ayaa si aad ah uga hooseeya bukaanada GHD marka loo eego shakhsiyaadka caafimaadka qaba