JWH18 Jwh18 5cl Sgt78 7A 7ad Adb S709 CAS 209414-07-3

JWH-018 (1-pentyl-3-(1-naphthoyl)indole, NA-PIMO poʻo AM-678) o se vailaʻau faʻamaʻi i totonu o le aiga naphthoyl indole, lea o loʻo faʻaalia i CB 1 ma CB 2 cannabinoid receptors, E iai le mautinoa. filifili mo CB 2. E maua ai aʻafiaga i manu e pei o le THC, o se cannabinoid e maua faʻanatura i le cannabis, e taʻitaʻia ai lona faʻaogaina i oloa gaosia o le cannabis, lea i nisi o atunuʻu o loʻo faʻatau faʻatulafonoina o "faʻafefiloi manogi."

I le avea ai o se agonist atoatoa mo CB 1 ma CB 2 cannabinoid receptors, o lenei tuufaatasiga ua faʻavasegaina o se analgesic.O aʻafiaga faʻamaʻi o le cannabinoid ligands faʻasalalau e CB1 faʻafeiloaʻi ua faʻaalia lelei i le togafitiga o tiga o le neuropathic, tiga o le kanesa, ma le gasegase.

O nei mea faʻapipiʻi e galue e ala i le faʻataʻitaʻiina o hormones endocannabinoid e masani ona tupu mai i le tino, e pei o le 2-AG ma le anandamide (AEA), o loʻo galue faʻaola ma e mafai ona faʻamalosia pe taofia le faʻailoga o neura.Talu ai e itiiti se mea e iloa e uiga i mafuaʻaga o faʻamaʻi tigaina, e tatau ona faʻatautaia atili suʻesuʻega ma atinaʻe aʻo leʻi mafai ona faʻaalia le gafatia o ia meaola.