Saina tuʻuina atu Lidocaine CAS 137-58-6 faʻatasi ai ma le tau sili
Fa'amatalaga Autu
soluble i le ethanol, eter, benzene, chloroform ma le suauu, e le mafai ona solu i le vai.E masani ona faʻaaogaina le hydrochloride faavae, lidocaine hydrochloride (C14H22N2O·HCL, [73-78-9]) o se paʻepaʻe tioata paʻepaʻe.O le mea liusuavai o le 127-129 ℃, ma le mea faʻafefete ole monohydrate ole 77-78 ℃.E sili ona solu i le vai, 0.5% vai pHO4.0-5.5.Le manogi, tofo oona hemp.
Fa'aoga
O le oloa o se vaila'au fa'apitonu'u amide.E faʻaaogaina lautele i faʻamaʻi luga, faʻamaʻi infiltration, faʻamaʻi faʻamalosi ma faʻamaʻi epidural.Ole LD50 ole lidocaine hydrochloride ole 290mg/kg.
O talosaga fa'afoma'i e aofia ai fa'ama'i infiltration, fa'ama'i fa'ama'i epidURAL, fa'ama'i fa'asolosolo (e aofia ai fa'ama'i mucosal i le taimi o le thoracoscopy po'o le taotoga o le manava), ma le poloka neura.E mafai ona fa'aopoopo le epinephrine i le vai fa'ama'i e fa'aumi ai le taimi ole fa'ama'i ma fa'aitiitia ai a'afiaga e pei ole oona ile lidocaine.
Lidocaine e mafai foʻi ona faʻaaogaina e togafitia ai faʻamaʻi ventricular pe a maeʻa faʻalavelave faʻafuaseʻi, e aofia ai faʻalavelave faʻafuaseʻi ventricular, tachycardia ventricular, ventricular arrhythmias e mafua mai i le oona numera, taotoga o le fatu ma le faʻamaʻiina o le fatu, e aofia ai faʻamaʻi vave ventricular, tachycardia ventricular ma fibrillation ventricular.E faʻaaogaina foi i tagata mamaʻi e maua i le tulaga epilepticus e le tali atu i isi faʻamaʻi faʻamaʻi ma mo faʻamaʻi faʻapitonuʻu poʻo intraspinal.E masani ona le aoga i le supraventricular arrhythmias.
Fa'amatalaga
| Igoa Oloa | Lidocaine |
| CAS | 137-58-6 |
| MF | C14H22N2O |
| MW | 234.34 |
| EINECS | 205-302-8 |
| Liu liusuavai | 66-69°C |
| Fa'apuna | bp4 180-182°;bp2 159-160° |
| mafiafia | 0.9944 (fa'atatau fa'atatau) |
| fa'asino fa'asino | 1.5110 (fa'atatau) |
| Fp | 9℃ |
| vevela vevela. | Faleoloa ile RT |
| solubility | ethanol: 4 mg/mL |
| pka | pKa 7.88(H2O)(Fa'atatau) |
| fomu | pauta |
| lanu | Pa'epa'e i sina samasama |
| Suavai Solubility | e toetoe lava a le mafai ona solu |
| Merck | 14,5482 |
| Maumau: | Stable.E le fetaui ma vailaʻau faʻamaʻi malosi. |
| InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| CAS Fa'amaumauga Fa'amaumauga | 137-58-6(Fa'amatalaga Fa'amaumauga a le CAS) |