Xylazine CAS OYA: 7361-61-7 Rompun, Anased, Sedazine, Chanazine

Gukoresha ubuvuzi
Toluene thiazide ikunze gukoreshwa nko gutuza, kuruhura imitsi no gusesengura.Bikunze gukoreshwa mu kuvura tetanusi.Xylazine isa cyane nibiyobyabwenge nka phenothiazine, antidepressants ya tricyclic na clonidine.Nka anestheque, ikoreshwa kenshi hamwe na ketamine.Xylazine bigaragara ko igabanya umubiri kumva insuline no gufata glucose.Yohimbine ni alpha2 adrenergic reseptor antagonist yakoreshejwe mu kugabanya urugero rwa glucose kurwego rwiza.Yohimbine ihindura ingaruka za toluene thiazide mugihe cyamavuriro iyo itanzwe mumitsi nyuma gato ya toluene thiazide itanzwe

farumasi

Xylazine ni alpha ikomeye 2 adrenergic agonist.Toluene thiazide hamwe na alpha2 adrenergic reseptor agonist ikwirakwizwa mumubiri muminota 30-40 iyo yatanzwe.Bitewe na lipofilique nyinshi, toluene thiazide itera mu buryo butaziguye reseptor yo hagati ya α2 kimwe na reseptor ya αadrenergic yakira mubice bitandukanye.Nka agonist, toluene thiazide itera kugabanuka kwa neurotransmission ya norepinephrine na dopamine muri sisitemu yo hagati.Irabikora yigana guhuza norepinephrine na autoreceptors hejuru ya presinaptic, bikavamo guhagarika ibitekerezo bya norepinephrine.

X.Rero, toluene thiazide yiyongereye cyane K m kandi ntabwo byagize ingaruka kuri V max.Ibi birashobora kubaho binyuze muburyo butaziguye n'uturere twuzuzanya na antidepressant ihuza imbuga.Kurugero, toluene thiazide na clonidine bibuza gufata MIBG (analogue ya norepinephrine) na selile neuroblastoma.Xylazine ifite aho ihuriye na cholinergique, serotonergique, dopaminergique, alpha1, adrenergique, H 2-histamine, hamwe na reseptor ya opioid.Imiterere yimiti isa cyane na fenothiazine, antidepressants ya tricyclic na clonidine