Trenbolone Cyclohexylmethylcarbonate CAS: 23454-33-3 11-trien-3-imwe ya karubone cyclohexylMethylcarbonate (8CI)

Intangiriro muri make:
Trenbolone (TRE) ni imisemburo ya steroid protein ikoreshwa cyane.Nibikomoka kuri chemosynetique bisa na hormone yumuntu wumugabo testosterone mumiterere no mubikorwa.Irashobora guteza imbere intungamubiri za poroteyine, kongera ubushake bwo kurya, kongera imitsi, gutera calcium na fosifore mu ngingo z’amagufwa, kandi irashobora gukoreshwa mu buvuzi kugira ngo ivure ibura ry’imirire ikabije na osteoporose, ariko kandi ni n'ubwoko bukoreshwa cyane mu gukangura siporo.Itsinda bolone cyclohexyl methyl karubone irashobora gukoreshwa nkurwego rwo hagati rwitsinda Bolone.
Imyiteguro:
Itsinda bromcyclohexyl methyl karubone yateguwe kuburyo bukurikira:
3G17 / 3-hydroxy-estradiol-4,9, 11-triene-3-imwe yashongeshejwe muri pyridine kuri 15 ℃ na 0 ℃ kubera imyigaragambyo hamwe nikirere cya azote.Komeza ubushyuhe buri hagati ya dogere selisiyusi 0 na 10.Buhoro buhoro ongeramo buhoro buhoro 50ml hexahydrobenzyl chloride ya Chemical Book, hanyuma ushyushya imvange yose kubushyuhe bwibidukikije, ukangure amasaha 2, hanyuma ukonje kugeza kuri 0 ° C. Ongeramo triethylamine hanyuma ukangure muminota 30 kugirango uzamure ubushyuhe mubidukikije hanyuma usukemo imvange ya reaction mubivange. kuvanga amazi / urubura.Yakuweho na methylene chloride, hanyuma icyiciro kama kwozwa namazi kugirango kidafite aho kibogamiye, cyumishwa na sodium sulfate, hanyuma kigahumeka munsi yumuyaga kugeza cyumye.Ibisigisigi byatandukanijwe na chromatografiya kuri gelika ya silika, bivangwa na 4: 1 bivanze na benzene / Ethyl acetate, hanyuma byongera gushyirwaho bivuye muri isopropyl ether / hexane ivanze.Chromatografiya yongeye gukorwa kuri gelika ya silika, ivangwa hamwe nuruvange rwa benzene / Ethyl acetate, hanyuma amaherezo yongeye gushyirwa muri cyclohexane na peteroli ether kugirango ibone 1.60g groupe bromcyclohexyl methyl karubone.Ibicuruzwa bigaragara nka prism iboneka muri Ethanol, ether, benzene, acetone, na chloroform, ariko ntibishobora gushonga mumazi, acide acide, hamwe nibisubizo bya lye.