Polypeptide API Ifu Ubwiza Peptide Ibicuruzwa Byimiti Ikigega kinini Alarelin CAS 79561-22-1 kuburumbuke

Alarelin CAS 79561-22-1Ikoreshwa:

Alarelin (gonadotrophine irekura imisemburo analogue (GnRH-A), izwi kandi ku izina rya alanine, ni analtaque ya nonapeptide analogue ya hormone irekura gonadotropine (GnRH), kandi ingaruka zayo zibiyobyabwenge zikubye inshuro 15 iy'umubyeyi. Irashobora gutera glande ya pitoito. icyiciro cya mbere cyimiti Kurekura imisemburo ya luteinizing (LH) hamwe na hormone itera imisemburo (FSH), bigatuma ubwiyongere bwigihe gito bwimisemburo ikomoka kuri ovarian ikomoka kumasemburo ya steroid inshuro nyinshi bishobora kubuza irekurwa rya LH na FSH muri glande ya pitoito, bikagabanya urwego ya estradiol mu maraso, igera kuri ovariectomy yibiyobyabwenge Muri icyo gihe, igira ingaruka ku mikorere ya kanseri ya endometrale ifitanye isano na oncogène ras, neu, na myc. Ivuriro, rikoreshwa cyane cyane mu kwinjiza ovulation, kuvura ubugumba biterwa na imikorere idasanzwe yintanga, endometriose na fibroide nyababyeyi nibindi kandi byongera umuvuduko wo gutwita.

Alarelin ni sintetike ya nonapeptide analogue ya hormone irekura gonadotropine (GnRH), ishobora gutera glande ya pitoito kurekura imisemburo ya luteinizing (LH) hamwe na hormone itera imisemburo (FSH) mugihe cyambere cyimiti, bigatuma ubwiyongere bwigihe gito bwintanga ngore- imisemburo ikomoka kuri steroid hormone Book Book; imiti isubirwamo irashobora kubuza irekurwa rya LH na FSH muri glande ya pituito, kugabanya urugero rwa estradiol mumaraso, kandi bikagera ku ngaruka za ovariectomy.Izi ngaruka zo kubuza zishobora gukoreshwa mu kuvura indwara ziterwa na hormone nka endometriose.

Mubuvuzi, bukoreshwa cyane cyane mu gutera intanga ngore, kuvura ubugumba buterwa n'imikorere idasanzwe yintanga ngore, endometriose na fibroide nyababyeyi, nibindi, no kuzamura umuvuduko wo gutwita.