Organic Chemical Raw Material Factory Yapamwamba Yapamwamba Mwachindunji Tumitsira Troparil CAS 74163-84-1 Pofufuza

Troparil ndi phenyltropane-based dopamine reuptake inhibitor yomwe imachokera ku methylecgonidine.Ndi mankhwala olimbikitsa omwe amagwiritsidwa ntchito pofufuza zasayansi.Mtundu wogwiritsidwa ntchito kwambiri wa troparil ndi mchere wa tartrate, koma mchere wa hydrochloride ndi naphthalenedisulfonate umapezekanso, komanso maziko aulere.
Troparil imagwiritsidwa ntchito pofufuza zasayansi mu dopamine reuptake transporter.Mitundu ya 3H-radiolabelled ya troparil yakhala ikugwiritsidwa ntchito mwa anthu ndi nyama kupanga mapu ogawa ma dopamine transporters muubongo.Amagwiritsidwanso ntchito pofufuza nyama.
Troparil ndi yamphamvu kangapo kuposa cocaine monga dopamine reuptake inhibitor, koma imakhala yocheperako ngati serotonin reuptake inhibitor, ndipo imakhala ndi nthawi yotalikirapo kangapo, popeza mphete ya phenyl imalumikizidwa mwachindunji ndi mphete ya tropane kudzera munjira yomwe si- hydrolyzable carbon-carbon chomangira.Kupanda kulumikizana kwa ester kumachotsa mankhwala ochititsa dzanzi m'deralo, kotero kuti troparil ndi cholimbikitsa.Kusintha kumeneku kumapangitsanso kuti troparil ikhale yocheperako pang'ono kuposa cocaine.