Ipamorelin CAS: 170851-70-4 IPAMORELIN;AIB-HIS-D-NAL(2)-D-PHE-LYS-NH2
Whakamahinga
Ko te Ipamorelin (INN) (waehere whanaketanga NNC 26-0161) he agonist peptide-whiriwhiri o te auxin tuku peptides / somatosecretin receptors (GHS) me te somatosecretin.He pentapeptide me te raupapa waikawa amino Aib-His-D-2-Nal - D-Phe -Lys-NH 2, i ahu mai i te GHRP-1.
Ko te Ipamorelin te whakanui ake i nga taumata o te hormone tupu plasma (GH) i roto i nga kararehe me te tangata.I tua atu, ko te ipamorelin te whakatairanga i te taumaha i roto i nga kararehe.Ka rite ki te pralmorelin me te GHRP-6, kaore te ipamorelin e pa ki te prolactin, te hormone whakaihiihi follicle (FSH), te hormone luteinizing (LH), te taumata thyrotropin (TSH) ranei.Engari, kaore i rite ki te pramoline (GHRP-2) me te GHRP-6, engari he rite tonu ki te tipu o te hormone releasing hormone (GHRH), kaore te iparerelin e whakaihiihi i te whakawhitinga o te hormone adrenocorticotropic (ACTH) ranei cortisol me te tino whiriwhiringa mo te whakauru i te GH secretion anake.
I whakawhanakehia tuatahi a Ipamorelin e Novo Nordisk me te whakahaere i nga whakamatautau haumanu i te waahanga II hei maimoatanga mo te ilobstruction i muri i te mahi, engari i whakamutua na te kore o te kaha.
Kua whakamahia a Ipamorelin e nga kaipara hei tarukino whakarei ake i te mahi.
