NO CAS;1631074-54-8 SGT-78 CUMYL-4CN-BINACA CUMYL-CYBINACA

Ko te CUMYL-4CN-BINACA (e mohiotia ana ko CUMYL-CYBINACA ranei SGT-78) he cannabinoid waihanga i runga i te indazol-3-formamide kua hokona i runga ipurangi hei rongoa motuhake.He agonist kaha mo nga kaiwhakawhiwhi cannabinoid CB 1 me CB 2, me nga uara in vitro EC 50 o 0.58 nM me 6.12 nM, ia.I roto i nga kiore, ko te CUMYL-4CN-BINACA e whakaputa ana i te hauhautanga me te whakapouri i te wiri na roto i te mahi a te kaiwhakawhiwhi CB 1, a ko nga purongo korero e whakaatu ana i te horopeta kaha mo te 0.1 mg i roto i te tangata.

Ko te CUMYL-4CN-BINACA ka whakakorikoria ki te whakaputa i te cyanide, ka puta he awangawanga mo te paitini ate.Kua puta tetahi keehi o te hyperthermia, te rhabdomyolysis me te mate whatukuhu e pa ana ki tana whakamahinga.