GHRP-2/Pralmorelin CAS: 158861-67-7 d-ala-β- (2-naphthyl) -d-ala-trp-d-phe-lys amide

Pralmorelin (INN) (aha ahia GHRP Kaken 100; KP-102, GPA-748, WAY-GPA-748), nke a makwaara dị ka pralmorelin hydrochloride (JAN) na pralmorelin dihydrochloride (USAN), na karịsịa, Uto. A na-eji hormone na-ewepụta Peptide 2 (GHRP-2), onye na-ahụ maka ihe na-eto eto (GHS), dị ka onye na-achọpụta ọrịa ma na-ere ya n'ụdị nhazi otu dose nke Kaken Pharmaceutical nke Japan maka ntule nke ụkọ hormone uto (GHD).

Pralmorelin bụ ọgwụ peptide sịntetịt nwere ọrụ ọnụ.Kpọmkwem, ọ bụ ihe analọg nke methoxyenkephalin na amino acid usoro D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Ọ na-eme dị ka auxin na-ahapụ peptide / uto hormone secretin anabata (na-anabata). GHSR) agonist na ọ bụ ọgwụ mbụ ụdị ya ewebata n'ụlọọgwụ.Nlekọta ọgwụ siri ike na-abawanye ọkwa nke homonụ na-eto plasma (GH) na ntụkwasị obi na-ebute agụụ ma na-abawanye oriri mmadụ.

A na-amụkwa Pralmorelin maka GHD na mkpụmkpụ dị mkpụmkpụ (pituitary dwarfism) wee banye na usoro nke II ụlọ ọgwụ maka ihe ngosi ndị a, mana n'ikpeazụ emebeghị ya n'ahịa.Nke a nwere ike ịbụ n'ihi na ikike pramoline ịbawanye ọkwa plasma GH dị ala nke ukwuu na ndị ọrịa GHD karịa ndị nwere ahụike