Sarm S4 Andarine Yellow ntụ ntụ

Andarine (S-4) bụ arylpropionamide-enwetara onyinye [S-3- (4-acetylamino-phenoxy) -2-hydroxy-2-methyl-N- (4-nitro-3-trifluoromethyl-phenyl) -propionamide] mbụ. kọwara site Yin et al.ịbụ onye na-ahọrọ androgen receptor modulator (SARM).E gosipụtara Andarine (S-4) site na in vitro na ọmụmụ vivo ka ọ bụrụ agonist anabolic dị irè, na-enweghị mmetụta-akụkụ na-ejikọta ya na anabolic-androgenic steroid, na-ejikọta isi na njedebe maka 5a-reductase iji mepụta DHT na prostate.
Ọrụ ọgwụ nke andarine na-atụ aro ike dị ukwuu nke andarine na mmepe nke SARM dị na ụlọ ọgwụ, nke na-enye uru ọgwụgwọ pụrụ iche karịa ndị otu steroid ha na ohere na-akpali akpali iji chịkwaa mmetụta androgen dị iche iche na anụ ahụ dị iche iche, si otú a na-ebelata nnyonye anya na nkịtị. .Ya mere, andarine na-ekwe nkwa na ule ụlọ ọgwụ dị elu nke na-achọ ịgwọ ọrịa ndị metụtara afọ yana igbochi mgbaàmà nke ọrịa siri ike dị ka sarcopenia na ọrịa cancer cachexia.
Andarine bụ agonist nke anaghị anabata androgen receptor (AR) nwere Ki nke 4 nM.Andarine na-egosipụta ọrụ anabolic dị ike ma dị irè ma na-ebute mkpali na-adabere na dose nke uto na prostate, seminal vesicles, n'otu n'otu.Andarine nwere mmetụta antiosteoporotic nwere ike.
Andarine (nke a na-akpọbu GTx-007; S-4; GTx007; S4) bụ onye na-eme ihe na-edozi ahụ na onye na-ahọrọ agonist na-abụghị steroidal androgen receptor (AR), kpọmkwem onye na-eme ihe na-eme ka androgen receptor modulator (SARM), nke nwere ike ịba uru na imebi ahụ ike. na osteoporosis.Ọ na-eji Ki nke 4 nM rụọ ọrụ AR ma bụrụ anụ ahụ-ahọpụtara maka akụkụ ahụ anabolic.A na-enyocha Andarine maka ọgwụgwọ ọnọdụ ndị dị ka ịla n'iyi anụ ahụ, osteoporosis na hypertrophy prostatic na-adịghị mma.Na ụdị anụmanụ nke benign prostatic hypertrophy, e gosiri andarine iji belata prostate arọ na mmetụta yiri nke finasteride, ma na-enweghị na-emepụta ọ bụla mbelata na muscle uka ma ọ bụ mgbochi-androgenic mmetụta.