GHRP-2/Pralmorelin CAS: 158861-67-7 d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide

Pralmorelin (INN) (lub npe lag luam GHRP Kaken 100; Yav dhau los txoj kev loj hlob code npe KP-102, GPA-748, WAY-GPA-748), tseem hu ua pralmorelin hydrochloride (JAN) thiab pralmorelin dihydrochloride (USAN), thiab tshwj xeeb, Kev Loj Hlob Cov tshuaj hormone tso tawm Peptide 2 (GHRP-2), ib qho kev loj hlob hormone secretagotor (GHS), yog siv los ua tus neeg saib xyuas kev kuaj mob thiab ua lag luam nyob rau hauv ib koob tshuaj formulation daim ntawv los ntawm Kaken Pharmaceutical ntawm Nyiv rau kev ntsuam xyuas ntawm kev loj hlob hormone deficiency (GHD).

Pralmorelin yog tshuaj peptide hluavtaws nrog rau qhov ncauj.Tshwj xeeb, nws yog ib qho analogue ntawm methoxyenkephalin nrog amino acid sequence D-Ala-D -(β-naphthyl) -ala-trp-d-phe -Lys-NH 2. Nws ua raws li auxin tso peptide / loj hlob hormone secretin receptor ( GHSR) agonist thiab yog thawj cov tshuaj ntawm nws hom uas yuav tsum tau nkag mus rau hauv tsev kho mob.Kev tswj hwm ntawm cov tshuaj no ua rau muaj kev loj hlob ntawm cov tshuaj hormones hauv plasma (GH) thiab txhim kho kev tshaib kev nqhis thiab nce kev noj zaub mov rau tib neeg.

Pralmorelin tseem raug kawm rau GHD thiab luv luv stature (pituitary dwarfism) thiab nkag mus rau theem II kev kuaj mob rau cov kev qhia no, tab sis thaum kawg tsis tau ua rau kev lag luam.Qhov no tej zaum yuav yog vim hais tias pramoline lub peev xwm los nce plasma GH qib qis dua hauv cov neeg mob GHD dua li cov neeg noj qab haus huv.