Epithalon CAS:307297-39-8 EpithalonAcetate Glycine 55 i ʻōlelo ʻia he protein
Hoʻohana
Ua ʻike ʻia kahi noiʻi in vivo o nā ʻiole ʻelemakule ua hoʻemi nui ka mālama ʻana i ka epitalon i ka ulu ʻana o nā aberrations chromosomal ma nā ʻiole ʻano ʻāhiu a me nā ʻiole i hōʻike ʻia e kahi phenotype ʻelemakule wikiwiki, i kūlike me ka piʻi ʻana o ka lōʻihi telomere.
ʻO kekahi noiʻi ʻana i nā ʻiole kahiko i ʻike ʻia ua hoʻonui ka epitalon i ka hana o ka antioxidant enzymes superoxide dismutase, glutathione peroxidase, a me ka glutathione -S-transferase.
Ma nā hoʻokolohua me nā ʻiole wahine C3H/He hoʻokahi makahiki, ua hoʻemi ʻo Epitalon i ka helu o nā maʻi maʻi kūʻokoʻa a me ka helu o nā metastases i nā ʻiole i hoʻomohala i nā maʻi maʻi kūlohelohe, a ua manaʻo ʻia e loaʻa i ka mea hoʻomake a me nā waiwai anti-metastatic.
Ma ke aʻo ʻana i nā moa e hana ana i ka pituitectomy neonatal a ma hope o ka maturation, ua hoʻoikaika ʻo epitalon i ka hoʻihoʻi ʻana i ke ʻano morphological o ka thymus, a me ke ʻano a me ka hana o ka thyroid gland.
ʻIke ʻia ʻo Epitalon e hoʻonui i ka hoʻonui ʻana o nā lymphocyte i loko o ka thymus, me ka hoʻonui ʻana paha i ka interferon gamma i hana ʻia e nā cell T.
Ua hōʻike ʻia kekahi noiʻi ʻana i nā ʻiole kahiko i ka hoʻonui ʻia ʻana o ke ola o nā ʻiole.
